University of Babylon Discusses a Diploma Thesis on Thalassemia Patients The Department of Family and Community Medicine at the College of Medicine, University of Babylon, held the defense of a high diploma thesis by student Tamara Haider Diaa, titled “The Role of Cystatin C as an Early Marker of Renal Dysfunction in Beta-Thalassemia Patients with Iron Overload”, under the supervision of Dr. Ahmed Abdulmohsen Fakhri. The researcher explained that the study aimed to evaluate the value of cystatin C as an early biomarker of renal dysfunction in pediatric patients with iron overload in beta-thalassemia major, and to investigate the clinical factors associated with this dysfunction. This cross-sectional study was conducted at the Babylon Center for the Management of Hereditary Blood Diseases and demonstrated that cystatin C is a more sensitive biomarker than serum creatinine for early detection of renal impairment in iron-overloaded beta-thalassemia major patients. The study showed a significant elevation in cystatin C levels in these patients, even before abnormalities appeared in conventional indicators such as serum creatinine. This finding highlights cystatin C’s essential role in early prediction and monitoring of renal dysfunction, allowing timely interventions to prevent further deterioration. In addition, the study found that demographic factors such as age and duration of blood transfusion therapy influence the progression of renal impairment, emphasizing the need for continuous monitoring of high-risk groups.
By: Zahraa Khawwam Abdulwahid
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