Media University of Babylon - Faculty of Medicine

Master’s Thesis on Bladder Cancer at the University of Babylon
The Department of Pharmacology and Toxicology at the College of Medicine, University of Babylon, discussed the master’s thesis of Suhad Hussein Atshan, titled:
“Development and Characterization of an In-Vitro Pharmacokinetic/Pharmacodynamic (PK/PD) Model Using Bladder Cancer Cell Lines to Evaluate Combination Anticancer Therapy”
under the supervision of Professor Dr. Hussam Wahab Sahib.
During her defense, the researcher explained that bladder cancer is one of the most frequently diagnosed malignancies worldwide, particularly among the elderly. Urothelial carcinoma accounts for more than 90% of cases. Its incidence is influenced by several risk factors, including cigarette smoking, exposure to industrial chemicals, and chronic urinary tract infections.
Standard treatment modalities include transurethral resection, intravesical chemotherapy or immunotherapy, systemic chemotherapy, and, more recently, immune checkpoint inhibitor therapy.
Despite these advances, disease recurrence and treatment resistance remain major challenges. Therefore, predictive and reproducible in-vitro PK/PD models are of growing importance for optimizing therapeutic regimens and designing appropriate drug combinations. .

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Media University of Babylon - Faculty of Medicine
Media University of Babylon - Faculty of Medicine