Media University of Babylon | College of Medicine, University of Babylon Discusses a PhD Dissertation

Media University of Babylon - Faculty of Medicine

College of Medicine, University of Babylon Discusses a PhD Dissertation

By : Zaynab Kadhim Ameen Awadh

Date : 16/2/2026 50:42:10 AM

College of Medicine, University of Babylon Discusses a PhD Dissertation
The College of Medicine at the University of Babylon witnessed the PhD dissertation defense of the student Dunya Mohammed Mubder Al-Birmany, entitled:
“Effect of biosynthesized silver nanoparticles from Pseudomonas aeruginosa on carbapenemase and selected virulence genes in Klebsiella pneumoniae.”
The defense was attended by Prof. Dr. Mohend Abbass Al-Shalah, Dean of the College of Medicine, Prof. Dr. Lamees Abdulrazzaq Abdul Latif, Head of the Microbiology Department, along with a distinguished group of faculty members and postgraduate students.
The Examination Committee
• Prof. Dr. Mohammed Abdul-Kadhim Hassan (University of Babylon / College of Medicine) – Chair
• Prof. Dr. Jawad Kazim Trad (University of Babylon / College of Medicine) – Member
• Prof. Dr. Baydaa Aboud Hassan (University of Kufa / College of Science) – Member
• Prof. Dr. Sura Ahsan Abd (University of Babylon / College of Science) – Member
• Prof. Dr. Ali Hadi Al-Dhabhawi (University of Babylon / College of Medicine) – Member
• Prof. Dr. Bushra Jabbar Hamoud (University of Babylon / College of Medicine) – Member & Supervisor
• Asst. Prof. Dr. Rabee’ Mohsen Hassani (University of Babylon / College of Medicine) – Member & Supervisor
Study Overview and Key Findings
The study introduced an innovative approach by using Pseudomonas aeruginosa to biologically synthesize silver nanoparticles and evaluate their effects on virulence genes and carbapenemase resistance in Klebsiella pneumoniae.
The biosynthesized silver nanoparticles demonstrated a strong ability to inhibit the growth of Klebsiella pneumoniae and had a direct impact on both virulence genes and carbapenemase-related resistance.
A total of 100 isolates were isolated and confirmed with a 99.7% match using the VITEK-2 system, with absolute resistance (100%) recorded against several conventional antibiotics. The results also showed that combining nanoparticles with antibiotics significantly enhanced the efficacy of beta-lactams and carbapenems.
Molecular analysis revealed the presence of virulence and resistance genes (such as blaNDM and blaKPC), with 79 point mutations identified and a 99% global genetic similarity reported.
Conclusion
At the end of the session, the committee praised the scientific rigor and outstanding research effort of the researcher Dunya Mohammed Mubder Al-Birmany, under the supervision of Prof. Dr. Bushra Jabbar Hamoud and Asst. Prof. Dr. Rabee’ Mohsen Hassani, emphasizing that the findings represent a valuable contribution and open new horizons for the use of nanotechnology in combating resistant bacterial strains.